Peptides: The Science, Uses & Safety | Dr. Abud Bakri
Dr. Abud Bakri, MD, is a board-certified internal medicine physician and expert in the science and clinical use of peptides. We discuss the history, uses, sourcing and safety of BPC-157, GHK-Cu, pinealon, epithalon, GLP-1s, retatrutide, melanotan and growth hormone-promoting peptides. We discuss the gap that exists between animal and human data and meaningful differences in the sources for different peptides. For those interested in peptides, Dr. Bakri provides a grounded look at the science, risks and uncertainties shaping the field today.
Articles
- A new gastric juice peptide, BPC. An overview of the stomach-stress-organoprotection hypothesis and beneficial effects of BPC (Journal of Physiology-Paris)
- Gastric pentadecapeptide BPC 157 accelerates healing of transected rat Achilles tendon and in vitro stimulates tendocytes growth (Journal of Orthopaedic Research)
- Achilles detachment in rat and stable gastric pentadecapeptide BPC 157: promoted tendon-to-bone healing and opposed corticosteroid aggravation (Journal of Orthopaedic Research)
- Pinealon increases cell viability by suppression of free radical levels and activating proliferative processes (Rejuvenation Research)
- Health consequences of thymus removal in adults (The New England Journal of Medicine)
- Thymic health consequences in adults (Nature)
- Reversal of epigenetic aging and immunosenescent trends in humans (Aging Cell)
- Chemical characterization of thymosin beta 4 (Journal of Biological Chemistry)
- Human whole-blood NAD+ levels do not vary with age or lifestyle interventions (Nature Metabolism)
- Protective effects of GHK-Cu in bleomycin-induced pulmonary fibrosis via anti-oxidative stress and anti-inflammation pathways (Life Sciences)
- Longer wavelengths in sunlight pass through the human body and have a systemic impact which improves vision (Scientific Reports)
- Early onset of reproductive function in normal female mice treated with leptin (Science)
Other Resources
Huberman Lab Episodes Mentioned
- Dr. Diego Bohórquez: The Science of Your Gut Sense & the Gut-Brain Axis
- Restore Youthfulness & Vitality to the Aging Brain & Body | Dr. Tony Wyss-Coray
- How to Control Your Cortisol & Overcome Burnout
- Dr. Samer Hattar: Timing Light, Food, & Exercise for Better Sleep, Energy & Mood
- Dr. Zachary Knight: The Science of Hunger & Medications to Combat Obesity
People Mentioned
- Ivan Pavlov: physiologist, Nobel laureate
- Hans Selye: endocrinologist, stress theory
- Vladimir Gulevich: biochemist
- Brigham Buhler: founder of Ways2Well
- Robert Breedlove: podcaster, Bitcoin
- Vladimir Khavinson: gerontologist
- Harvey J. Karten: comparative neuroanatomist
- Santiago Ramón y Cajal: neuroanatomist, Nobel laureate
- Edward Jones: neuroanatomist
- Robert Sapolsky: neurobiologist
- Rudolf Virchow: pathologist
- Allan L. Goldstein: biochemist
- Loren Pickart: researcher, copper peptides
- Sam Altman: CEO, OpenAI
This transcript is currently under human review and may contain errors. The fully reviewed version will be posted as soon as it is available.
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