Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard
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Dr. Martin Picard, PhD, is a professor of behavioral medicine at Columbia University and an expert on how our behaviors and psychology shape cellular energy production and rates of aging. He explains that your mitochondria don’t just “make energy”; they translate what you do—your mindset and your relationships—into the energy you experience as vitality or lack thereof. He explains how exercise, nutrition, sleep, meditation, and even certain thought patterns and our sense of purpose can charge our cells like batteries. He also shares findings that hair greying is the result of cellular stress and is reversible. This episode links physical and mental ‘energy’ with cellular energy and provides science-supported tools to improve your physical and mental health.
Articles
- A human brain map of mitochondrial respiratory capacity and diversity (Nature)
- Features of a successful therapeutic fast of 382 days' duration (Postgraduate Medical Journal)
- Mitochondrial function in the brain links anxiety with social subordination (Proceedings of the National Academy of Sciences of the United States of America)
- Quantitative mapping of human hair greying and reversal in relation to life stress (eLife)
- Metabolic regulation of species-specific developmental rates (Nature)
- Mitochondria metabolism sets the species-specific tempo of neuronal development (Science)
- Daily energy expenditure through the human life course (Science)
- Ponsegromab for the Treatment of Cancer Cachexia (New England Journal of Medicine)
- Cellular allostatic load is linked to increased energy expenditure and accelerated biological aging (Psychoneuroendocrinology)
- Voluntary hypometabolism in an indian yogi (Journal of Thermal Biology)
- Transcendental Meditation to combat psychosocial stress, hypertension and cardiovascular disease (Nature Reviews Cardiology)
Other Resources
- Human Genome Project
- NSDR
- Joe Rogan Experience #1901 - Steven Pressfield
- Is moderate drinking actually healthy? Scientists say the idea is outdated
- Waking Up app
- Baszucki group
Huberman Lab Episodes Mentioned
- How to Prevent & Treat Colds & Flu
- What Alcohol Does to Your Body, Brain & Health
- How to Overcome Inner Resistance | Steven Pressfield
- How to Optimize Fertility in Males & Females
People Mentioned
- Ben Barres: neuroscientist, Stanford University
- Richard Feynman: physicist, Nobel laureate
- Anna Monzel: research scientist, Picard lab
- Caroline Trumpff: professor of medical psychology, Columbia University
- Hazel Szeto: pharmacologist, entrepreneur

About this Guest
Dr. Martin Picard
Martin Picard, PhD, is a professor of behavioral medicine at Columbia University and a leading expert on how your behaviors and psychology shape cellular energy production and biological aging.
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