How Food Choices Shape Memory, Cognition & Cravings | Dr. Scott Kanoski
Dr. Scott Kanoski, PhD, is a Professor of Human and Evolutionary Biology and Neurobiology at the University of Southern California. We discuss how different foods impact memory and cognitive function as well as cravings. We also discuss how GLP-1 drugs work to control hunger in the brain and body, the role of the gut microbiome, and the effects of artificial and low calorie sweeteners on hunger and satiety. This episode highlights how nutrition impacts much brain health and learning capacity and how our memory impacts food choices too.
Articles
- Peripheral and central GLP-1 receptor populations mediate the anorectic effects of peripherally administered GLP-1 receptor agonists, liraglutide and exendin-4 (Endocrinology)
- Brain uptake pharmacokinetics of incretin receptor agonists showing promise as Alzheimer's and Parkinson's disease therapeutics (Biochemical Pharmacology)
- Intrameal hepatic portal and intraperitoneal infusions of glucagon-like peptide-1 reduce spontaneous meal size in the rat via different mechanisms (Endocrinology)
- Early-life low-calorie sweetener consumption disrupts glucose regulation, sugar-motivated behavior, and memory function in rats (JCI Insight)
- Recall of recent lunch and its effect on subsequent snack intake (Physiology & Behavior)
- Episodic memory and appetite regulation in humans (PLoS One)
- Different patterns of memory impairments accompany short- and longer-term maintenance on a high-energy diet (Journal of Experimental Psychology: Animal Behavior Processes)
- Effects of sucrose and high fructose corn syrup consumption on spatial memory function and hippocampal neuroinflammation in adolescent rats (Hippocampus)
- Consumption of processed foods impairs memory function through dietary advanced glycation end-products (bioRxiv)
- Early-life sugar consumption has long-term negative effects on memory function in male rats (Nutritional Neuroscience)
- Early-life sugar consumption affects the rat microbiome independently of obesity (The Journal of Nutrition)
- Gut microbial taxa elevated by dietary sugar disrupt memory function (Translational Psychiatry)
- Western diet consumption impairs memory function via dysregulated hippocampus acetylcholine signaling (Brain, Behavior, and Immunity)
- Gut vagal sensory signaling regulates hippocampus function through multi-order pathways (Nature Communications)
- Higher reported saturated fat and refined sugar intake is associated with reduced hippocampal-dependent memory and sensitivity to interoceptive signals (Behavioral Neuroscience)
- The vagus nerve promotes memory in rats via nutrient-induced septo-hippocampal acetylcholine signaling (Nature Communications)
- What causes humans to begin and end a meal? A role for memory for what has been eaten, as evidenced by a study of multiple meal eating in amnesic patients (Psychological Science)
- Hippocampal lesions impair retention of discriminative responding based on energy state cues (Behavioral Neuroscience)
- Medial nucleus tractus solitarius oxytocin receptor signaling and food intake control: the role of gastrointestinal satiation signal processing (American Journal of Physiology-Regulatory, Integrative and Comparative Physiology)
Books
- Dopamine Nation: Finding Balance in the Age of Indulgence by Anna Lembke
- The Molecule of More: How a Single Chemical in Your Brain Drives Love, Sex, and Creativity—and Will Determine the Fate of the Human Race by Daniel Z. Lieberman and Michael E. Long
Huberman Lab Episodes Mentioned
- How to Rewire Your Brain & Learn Faster | Dr. Michael Kilgard
- What Humans, Animals & Plants Tell Us About Consciousness | Michael Pollan
People Mentioned
- William Banks: Professor, Division of Gerontology and Geriatric Medicine, University of Washington
- Elizabeth Rhea: Research Assistant Professor, University of Washington
- Wolfgang Langhans: Professor Emeritus in Health Sciences & Technology, ETH Zurich
- Suzanne Higgs: Professor in the Psychobiology of Appetite, University of Birmingham
- Jeff Brunstrom: Professor of Experimental Psychology, University of Bristol
- George A. Bray: Professor Emeritus, Louisiana State University
- Richard Stevenson: Professor of Psychological Sciences, Macquarie University
- Michael Merzenich: Professor Emeritus, University of California, San Francisco
- Harvey Grill: Professor of Psychology, University of Pennsylvania
- Paul Rozin: Professor of Psychology, University of Pennsylvania
- Justin Sonnenburg: Professor of Microbiology and Immunology, Stanford University
This transcript is currently under human review and may contain errors. The fully reviewed version will be posted as soon as it is available.
Become a Huberman Lab Premium member to access full episode transcripts & more
Members also get to submit questions for AMA episodes, plus access to exclusive bonus content. A significant portion of proceeds are donated to fund human scientific research.
Become a Memberor sign in to Huberman Lab Premium
Huberman Lab Essentials are short episodes focused on essential science and protocol takeaways from past full-length Huberman Lab episodes.
Join 1M+ subscribers to get regular emails on neuroscience, health, and science-related tools from Dr. Andrew Huberman.
You'll also get Andrew's exclusive Daily Blueprint. In it, Andrew shares his daily routine. He also shares practical tools and protocols that you can use to stay productive and maximize your health.
