Essentials: Understanding & Healing the Mind | Dr. Karl Deisseroth

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In this episode of Huberman Lab Essentials, my guest is ⁠Dr. Karl Deisseroth, M.D., Ph.D.⁠, a clinical psychiatrist and professor of bioengineering and of psychiatry and behavioral sciences at Stanford University.

We discuss his experiences as a clinician treating complex psychiatric conditions and his lab’s pioneering work in developing transformative therapies for mental illness. He explains the complexities of mental illness and how emerging technologies—such as optogenetics and brain-machine interfaces—could revolutionize care. We also explore promising new therapies, including psychedelics and MDMA, for conditions like depression and PTSD.

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  • 00:00:00 Karl Deisseroth; Neurology vs Psychiatry
  • 00:01:36 Speech; Blood Test?; Seeking Help
  • 00:04:20 Feelings, Jargon; Psychiatric Treatment
  • 00:09:40 Future Treatment; Vagus Nerve Stimulation, Depression, Optogenetics
  • 00:18:24 Brain-Machine Interfaces
  • 00:19:37 ADHD Symptoms, Lifestyle, Technology
  • 00:26:10 Psychedelics, Depression Treatment, Risks
  • 00:32:19 MDMA (Ecstasy), Trauma & Post-Traumatic Stress Disorder (PTSD) Treatment
  • 00:35:21 Projections: A Story of Human Emotions Book, Optimism

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Huberman Lab Essentials

Dr. Karl Deisseroth: Understanding & Healing the Mind

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