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September 25, 2025

Essentials: Using Your Nervous System to Enhance Your Immune System

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In this ⁠Huberman Lab Essentials⁠ episode, I explain how the immune system defends against infection and describe the relationship between the immune and nervous systems.

I discuss the immune system's three primary layers of defense, emphasizing how each contributes to protection from infection. I share practical tools to enhance immune function and accelerate recovery from sickness, including specific breathing patterns, sleep positioning and targeted supplementation. I also explore the powerful mind-body connection, showing how mindset and nervous system activation can directly influence the body's ability to heal.

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People Mentioned

  • Asya Rolls: professor of life sciences, Tel Aviv University
  • Qiufu Ma: professor of neurobiology, Harvard Medical School
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  • 00:00:00 Immune System & Nervous System
  • 00:00:33 Immune System 101, Innate & Adaptive Immune Systems
  • 00:08:03 Mucus & Microbiome, Tools: Nasal Breathing; Avoid Eyes; Ingest Fermented Foods
  • 00:10:57 Sickness Behavior & Vagus Nerve, Fever, Photophobia, Rest
  • 00:15:35 Humoral Factors, Inflammatory Cytokines
  • 00:17:05 Sleep & Enhancing Immune System, Glymphatic System, Tool: Elevate Feet
  • 00:20:04 Stress & Inflammation, Tool: Early Symptoms & Cyclic Hyperventilation
  • 00:28:29 Positive Mindset & Immune Function, Dopamine
  • 00:31:22 Electroacupuncture, Fascia, Catecholamines & Inflammation
  • 00:33:42 Accelerating Recovery, Medication, Tool: Spirulina & Rhinitis
  • 00:35:53 Recap & Key Takeaways

This transcript is currently under human review and may contain errors. The fully reviewed version will be posted as soon as it is available.

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Huberman Lab Essentials

Using Your Nervous System to Enhance Your Immune System

Huberman Lab Essentials are short episodes focused on essential science and protocol takeaways from past full-length Huberman Lab episodes.

Join 800,000+ subscribers to get regular emails on neuroscience, health, and science-related tools from Dr. Andrew Huberman.

You'll also get Andrew's exclusive Daily Blueprint. In it, Andrew shares his daily routine. He also shares practical tools and protocols that you can use to stay productive and maximize your health.

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