In this episode, my guest is Dr. Sean Mackey, M.D., Ph.D., Chief of the Division of Pain Medicine and Professor of Anesthesiology, Perioperative and Pain Medicine and Neurology at Stanford University School of Medicine. His clinical and research efforts focus on using advanced neurosciences, patient outcomes, biomarkers and informatics to treat pain.
We discuss what pain is at the level of the body and mind, pain thresholds, and the various causes of pain. We also discuss effective protocols for controlling and reducing pain, including the use of heat and cold, acupuncture, chiropractic, physical therapy, nutrition, and supplementation.
We also discuss how pain is influenced by our emotions, stress and memories, and practical tools to control one’s psychological perception of pain.
And we discuss pain medications, including the controversial use of opioids and the opioid crisis.
This episode will help people understand, manage, and control their pain as well as the pain of others.
- Swearing as a response to pain (NeuroReport)
- Pain Mechanisms: A New Theory: A gate control system modulates sensory input from the skin before it evokes pain perception and response (Science)
- Sex differences in pain: a brief review of clinical and experimental findings (British Journal of Anaesthesia)
- Diffuse noxious inhibitory controls (DNIC). I. Effects on dorsal horn convergent neurones in the rat (Pain)
- Viewing Pictures of a Romantic Partner Reduces Experimental Pain: Involvement of Neural Reward Systems (PLOS ONE)
- Managing twin crises in chronic pain and prescription opioids (BMJ)
- The clinical use of mindfulness meditation for the self-regulation of chronic pain (Journal of Behavioral Medicine)
- Local immune response to food antigens drives meal-induced abdominal pain (Nature)
- Effect of Electroacupuncture vs Sham Treatment on Change in Pain Severity Among Adults With Chronic Low Back Pain: A Randomized Clinical Trial (JAMA Network Open)
- Mindfulness-Based Stress Reduction, Cognitive Behavioral Therapy, and Acupuncture in Chronic Low Back Pain: Protocol for Two Linked Randomized Controlled Trials (JMIR Research Protocols)
- Adverse Life Experiences and Brain Function: A Meta-Analysis of Functional Magnetic Resonance Imaging Findings (JAMA Network Open)
- Oral Treatment With α-Lipoic Acid Improves Symptomatic Diabetic Polyneuropathy: The SYDNEY 2 trial (Diabetes Care)
- United States National Pain Strategy for Population Research: Concepts, Definitions, and Pilot Data (The Journal of Pain)
About this Guest
Dr. Sean Mackey
Sean Mackey, M.D., Ph.D., is Chief of the Division of Pain Medicine and Professor of Anesthesiology, Perioperative and Pain Medicine and Neurology at Stanford University School of Medicine.
Join 400,000+ subscribers to get regular emails on neuroscience, health, and science-related tools from Dr. Andrew Huberman.
Plus, you’ll also get Andrew’s exclusive Daily Blueprint, where Andrew shares his daily routine, and outlines practical protocols you can use to stay productive and maximize your health.