Best Tools for Gut Health & Weight Loss | Dr. Chris Thompson
Dr. Chris Thompson, MD, Professor of Medicine at Harvard Medical School, Chief of Interventional Gastroenterology at Mass General Brigham in Boston, and Co-Director of the Center for Weight Management and Wellness, is a world-renowned expert on gastroenterology, metabolism, nutrition, and obesity medicine. He explains how your GI tract regulates hunger, fullness, and blood sugar, as well as the gut microbiome, metabolic health, and weight loss. We also discuss common GI tract issues and which particular tests or interventions are actually useful. We discuss both GLP-1 medications and non-GLP-1 approaches to weight loss. Given that gut health is vital to all the organs of the body, overall health, and longevity, our discussion ought to be of interest and practical value to everyone, including, of course, those struggling with gut health or weight loss challenges.
Articles
- Carbohydrate quality and human health: a series of systematic reviews and meta-analyses (The Lancet)
- Resistant starch decreases intrahepatic triglycerides in patients with NAFLD via gut microbiome alterations (Cell Metabolism)
- Gut-microbiota-targeted diets modulate human immune status (Cell)
- Ultra-Processed Diets Cause Excess Calorie Intake and Weight Gain: An Inpatient Randomized Controlled Trial of Ad Libitum Food Intake (Cell Metabolism)
- Trajectories of glycaemia, insulin sensitivity, and insulin secretion before diagnosis of type 2 diabetes: an analysis from the Whitehall II study (The Lancet)
- Prevalence of Optimal Metabolic Health in American Adults: National Health and Nutrition Examination Survey 2009–2016 (Metabolic Syndrome and Related Disorders)
- The mechanism of diabetes control after gastrointestinal bypass surgery reveals a role of the proximal small intestine in the pathophysiology of type 2 diabetes (Annals of Surgery)
- Duodenal Organoids From Metabolic Dysfunction-Associated Steatohepatitis Patients Exhibit Absorptive and Barrier Alterations (Gastro Hep Advances)
- Increased intestinal permeability and tight junction alterations in nonalcoholic fatty liver disease (Hepatology)
- Persistent metabolic adaptation 6 years after "The Biggest Loser" competition (Obesity)
- Partial jejunal diversion using an incisionless magnetic anastomosis system: 1-year interim results in patients with obesity and diabetes (Gastrointestinal Endoscopy)
- Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes (The New England Journal of Medicine)
Other Resources
Huberman Lab Episodes Mentioned
- Dr. Justin Sonnenburg: How to Build, Maintain & Repair Gut Health
- ADHD & How Anyone Can Improve Their Focus
People Mentioned
- Justin Sonnenburg: microbiome researcher; fermented foods and immune health
- Barry Marshall: physician and Nobel laureate; H. pylori and peptic ulcers
- Sheila Sherlock: physician and pioneer in hepatology
- William Brugge: gastroenterologist; Thompson’s mentor in endoscopic ultrasound
- Francesco Rubino: metabolic surgery researcher; foregut exclusion and diabetes
About this Guest
Dr. Chris Thompson
Chris Thompson, MD, is a Professor of Medicine at Harvard Medical School, Chief of Interventional Gastroenterology at Mass General Brigham in Boston, and Co-Director of the Center for Weight Management and Wellness.
This transcript is currently under human review and may contain errors. The fully reviewed version will be posted as soon as it is available.
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